Metabolism

Molecular basis of cellular senescence and aging

Lectures connecting senescence, p53 biology, metabolism, epigenetics and aging-related pathophysiology for Master-level biology and health students.

p53/E4F1-mediated metabolic and epigenetic control of senescence

Dissecting how p53-associated metabolic programs, pyruvate metabolism and acetyl-CoA production shape chromatin states and stabilize senescence during aging.