Publications

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M. Di Michele, A. Attina, P.F. Roux*, I. Tabet, S. Laguesse, J.Florido, M. Houdeville, A. Choquet, B. Encislai, G. Arena, C. De Blasio, O. Wendling, F.X. Frenois, L. Papon, L. Stuani, M. Fuentes, C. Jahannault Talignani, M. Rousseau, J. Guégan, Y. Buscail, P. Dupré, H.A. Michaud, G. Rodier, F. Bellvert, H. Kulyk, C. Ferraro Peyret, H. Mathieu, P. Close, F. Rapino, C. Chaveroux, N. Pirot, L. Rubio, A. Torro, T. Sorg, F. Ango, C. Hirtz, V. Compan, E. Lebigot, A. Legati, D. Ghezzi, L. Nguyen, A. David, C. Sardet, M. Lacroix, L. Le Cam. E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. In Nature Communications, 2025.

T. Sata, J. Nikolovski, R. Gould, I. Lboukili, P.F. Roux, G. Al-Ghalith, J. Orie, R. Insel, G. N. Stamatas. Skin surface biomarkers are associated with future development of atopic dermatitis in children with family history of allergic disease. In Skin Research & Technology, 2023.

G. N. Stamatas, P.F. Roux*, E. Boireau-Adamezyk, I. Lboukili, T. Oddos. Skin maturation from birth to 10 years of age: Structure, function, composition and microbiome. In Experimental Dermatology, 2023.

R. Y. Martinez-Zamudio, A. Stefa, J. de Freitas, T. Vasilopoulos, M. Simpson, G. Doré, P.F. Roux, M. A. Galan, R. J. Chokshi, O. Bischof, U. Herbig. Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars. In Cell Genomics, 2023.

A. Guerrero, A. Innes, P.F. Roux, S. Buisman, J. Jung, L. Ortet, V. Moiseeva, V. Wagner, L. Robinson, A. Ausema, A. Potapova, E. Perdiguero, E. Weersing, M. Aarts, N. Martin, T. Wuestefeld, P. Muñoz-Cánoves, G. de Haan, O. Bischof, J. Gil. 3-Deazaadenosine alleviates senescence to promote cellular fitness and cell therapy efficiency in mice. In Nature Aging, 2022.

T. Ondet, P.F. Roux, M. Monshouwer, G. Stamatas. Unlocking the mechanisms of Cutaneous Adverse Drug Reactions: Activation of the PI3K/AKT pathway by EGFR inhibitors triggers keratinocyte differentiation and polarization of epidermal immune responses. In JID Innovations, 2021.

P.F. Roux, T. Oddos, G. Stamatas. Deciphering the role of skin surface microbiome on skin health: an integrative multi-omics approach reveals three distinct microbial / metabolic clusters. In Journal of Investigative Biology, 2021.

C. Mangez, P.F. Roux, G. Stamatas, T. Oddos, C. Brun. An integrative multi-omic analysis reveals a major metabolic rewiring between baby foreskin keratinocytes and adult female abdominal keratinocytes. In Experimental Dermatology, 2021.

I. López, E. Chalatsi, S. Ellenbroek, A. Andrieux, P.F. Roux, J. Cerapio, G. Jouvion, J. van Rheenen, J. Seeler, A. Dejean. An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency. In Oncogene, 2020.

R. Martinez, P.F. Roux*, J. de Freitas, L. Robinson, G. Doré, B. Sun, D. Belenki, M. Milanovic, U. Herbig, C. Schmitt, J. Gil, O. Bischof. AP-1 imprints a reversible transcriptional programme of senescent cells. In Nature Cell Biology, 2020.

M. Seehawer, F. Heinzmann, L. D’Artista, P.F. Roux, L. Hoenicke, H. Dang, S. Klotz, L. Robinson, G. Doré, N. Rozenblum, T.W. Kang, R. Chawla, T. Buch, M. Vucur, M. Roth, J. Zuber, T.Luedde, B. Sipos, T. Longerich, M. Heikenwälder, X.W. Wang, O. Bischof, L. Zender. Necroptosis microenvironment directs lineage commitment in liver cancer. In Nature, 2018.

C. Désert, E. Baeza, M. Aite, M. Boutin, A. Le Cam, J. Montfort, M. Houée-Bigot, Y. Blum, P.F. Roux, C. Hennequet-Antier, C. Berri, S. Metayer-Coustard, A. Collin, S. Allais, E. Le Bihan, D. Causeur, F. Gondret, M. Duclos, S. Lagarrigue. Multi-tissue transcriptomic study reveals the main role of liver in the chicken adaptive response to a switch in dietary energy source through the transcriptional regulation of lipogenesis. In BMC Genomics, 2018.

R. Martínez-Zamudio, L. Robinson, P.F. Roux, O. Bischof. Snapshot: cellular senescence in pathophysiology. In Cell, 2017.

R. Martínez-Zamudio, L. Robinson, P.F. Roux, O. Bischof. Snapshot: cellular senescence pathways. In Cell, 2017.

E. Fernandez-Rebollo, B. Mentrup, R. Ebert, J. Franzen, G. Abagnale, T. Sieben, A. Ostrowska, P. Hoffmann, P.F. Roux, B. Rath, M. Goodhardt, J.M. Lemaitre, O. Bischof, F. Jakob, W. Wagner. Human platelet lysate versus fetal calf serum: these supplements do not select for different mesenchymal stromal sells. In Scientific Reports, 2017.

L. Frésard, S. Leroux, P.F. Roux, C. Klopp, D. Esquerré, P. Dehais, A. Djari, D. Gourichon, S. Lagarrigue, F. Pitel. Genome-wide characterization of RNA editing in chicken embryos reveals common features among vertebrates. In PLoS One, 2017.

K. Contrepois, C. Coudereau, B.A. Benayoun, N. Schuler, P.F. Roux, O. Bischof, R. Courbeyrette, C. Carvalho, J.Y. Thuret, Z. Ma, C. Derbois, M.C. Nevers, H. Volland, C.E. Redon, W.M. Bonner, J.F. Deleuze, C. Wiel, D. Bernard, M.P. Snyder, C.E. Rübe, R. Olaso, F. Fenaille, C. Mann. Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression. In Nature Communications, 2017.

C. Désert, E. Merlot, T. Zerjal, B. Bed’hom, S. Härtle, A. Le Cam, P.F. Roux, E. Baeza, F. Gondret, M.J. Duclos, S. Lagarrigue. Transcriptomes of whole blood and PBMC in chicken. In Comparative Biochemistry and Physiology, 2016.

P.F. Roux, S. Marthey, A. Djari, M. Moroldo, D. Esquerré, J. Estellé, C. Klopp, S. Lagarrigue, O. Demeure. Comparison of whole-genome (13X) and capture (87X) resequencing methods for SNP and genotype callings. In Animal Genetics, 2015.

P.F. Roux, L. Frésard, M. Boutin, S. Leroux, C. Klopp, A. Djari, D. Esquerré, P. Martin, T. Zerjal, D. Gourichon, F. Pitel, S. Lagarrigue. The extent of mRNA editing is limited in chicken liver and adipose, but impacted by tissular context, genotype, age and feeding as exemplified with a conserved edited site in COG3. In Genes Genomes Genetics, 2015.

J. Smith, D.W. Burt, the Avian RNAseq Consortium. Third report on chicken genes and chromosomes. In Cytogenetic and Genome Research, 2015.

P.F. Roux, S. Boitard, Y. Blum, B. Parks, A. Montagner, E. Mouisel, A. Djari, D. Esquerré, C. Désert, M. Boutin, S. Leroux, F. Lecerf, E. Le Bihan - Duval, C. Klopp, B. Servin, F. Pitel, M. Duclos, H. Guillou, A.J. Lusis, O. Demeure, S. Lagarrigue. Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation. In Genes Genomes Genetics, 2015.

P.F. Roux, M. Boutin, C. Désert, A. Djari, D. Esquerré, C. Klopp, S. Lagarrigue, O. Demeure. Re-sequencing data for refining candidate genes and polymorphisms in QTL regions affecting adiposity in chicken. In PLoS One, 2014.

K. Simonin - Le Jeune, A. Le Jeune, S. Jouneau, C. Belleguic, P.F. Roux, M. Jaguin, M.T. Dimanche - Boitrel, V. Lecureur, C. Leclerq, B. Desrues, G. Desruers, G. Brinchault, J.P. Gangneux, C. Martin - Chouly. Impaired function of macrophage from cystic fibrosis patients: CD11b, TLR-5 decrease and sCD24, inflammatory cytokines increase. In PLOS One, 2013.

S. Lagarrigue, L. Martin, F. Hormozdiari, P.F. Roux, A. van Nas, O. Demeure, A. Ghazalpour, E. Eskin, A.J. Lusis. Analysis of allele-specific expression in mouse liver by RNA-seq: a comparison with cis-eQTL identified using genetic linkage. In Genetics, 2013.